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Principal Enterprise Data Architect

Cellares

Cellares

IT
South San Francisco, CA, USA
USD 90k-210k / year
Posted on Apr 11, 2026
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Cellares is building a next-generation Integrated Digital Manufacturing Operations (IDMO) platform to enable scalable, GMP-compliant cell therapy manufacturing. As part of this transformation, we are establishing a modern enterprise data foundation powered by Databricks to unify data across engineering, manufacturing, quality, supply chain, finance and commercial systems.

We are seeking a Principal Enterprise Data Architect, a highly hands-on individual contributor who will design, build, and operationalize our enterprise data platform from the ground up.

This is a multidisciplinary role and this individual will play a critical role in enabling real-time decision-making, data governance, and AI readiness across the enterprise. This role is a startup-style builder (90% hands-on) and will evolve into a foundational leader for scaling data capabilities, including alignment with our Global Capability Center (GCC).

Candidates should enjoy working in a fast-paced, mission-driven environment, and be prepared to tackle a broad selection of challenges as the company grows.

Responsibilities

  • Architect and implement Databricks Lakehouse architecture
  • Build end-to-end ETL/ELT pipelines
  • Define canonical data models and scalable patterns
  • Integrate SAP S/4HANA, Tulip MES, LabVantage LIMS, Salesforce, and engineering systems
  • Align with API-first/event-driven architecture (MuleSoft / Workato)
  • Define data glossary, lineage, and quality frameworks
  • Implement Unity Catalog and governance aligned to GMP/21 CFR Part 11
  • Prepare datasets for analytics and AI/ML use cases
  • Support structured and unstructured data processing
  • Evaluate and implement BI tools (Sigma, Looker, Tableau)
  • Enable self-service analytics with governance
  • Build pipelines using Python, SQL, Spark
  • Establish reusable frameworks
  • Partner with engineering, manufacturing, quality, finance and software teams
  • Translate business needs into data solutions

Requirements

  • Bachelor’s or Master’s degree in Engineering, Life Sciences, Information Systems, or related field
  • 10+ years in data architecture/data engineering
  • Strong Databricks/Spark experience
  • Experience building data platforms from scratch
  • Integration with ERP/MES/LIMS/CRM systems
  • Azure cloud experience
  • Self-awareness, integrity, authenticity, and a growth/entrepreneurial mindset
This is Cellares
Cellares is the first Integrated Development and Manufacturing Organization (IDMO) and takes an Industry 4.0 approach to mass manufacturing the living drugs of the 21st century. The company is both developing and operating integrated technologies for cell therapy manufacturing to accelerate access to life-saving cell therapies. The company’s Cell Shuttle integrates all the technologies required for the entire manufacturing process in a flexible and high-throughput platform that delivers true walk-away, end-to-end automation. Cell Shuttles will be deployed in Cellares’ Smart Factories around the world to meet total patient demand for cell therapies at global scale. Partnering with Cellares enables academics, biotechs, and pharma companies to accelerate drug development and scale out manufacturing, lower process failure rates, lower manufacturing costs, and meet global patient demand.
The company is headquartered in South San Francisco, California with its commercial-scale IDMO Smart Factory in Bridgewater, New Jersey. The company is backed by world-class investors and has raised over $355 million in financing.
Leveling will be based on overall experience, education, and demonstration of knowledge throughout the interview process.

90000 - 210000 USD a year

Apply now
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